Linear atrophoderma of Moulin
نویسندگان
چکیده
CASE REPORT A 22-year-old Malay woman presented with an 11-year history of asymptomatic, unilateral brown patches affecting the right arm, right side of the trunk, and right leg. There were no prior skin lesions or inflammation. There was no significant medical or family history. Physical examination found linear hyperpigmented atrophic patches on the right arm, right trunk extending down to the right buttock, right thigh, and right leg following Blaschko’s lines involving both anterior and posterior aspects (Fig 1, A). The skin was slightly atrophic on palpation. No signs of induration or inflammation were noted (Fig 1, B). Laboratory investigations including full blood count, erythrocyte sedimentation rate, renal profile, liver function test, antinuclear antibodies, doublestranded antinuclear DNA antibodies, antieSCL-70 antibody, anti-SSA(Ro), anti-SSB(La), antieJo-1, and anti-RNP antibodies were all negative or within the normal range. The first skin biopsy from a hyperpigmented patch over the right arm found mild upper dermal perivascular lymphocytic infiltrate. No dermal sclerosis was seen. Skin biopsy was repeated from normal skin (Fig 2, A) and from the hyperpigmented patch (Fig 2, B) on the right arm. Histopathologic examination of the affected skin found a mild upper dermal perivascular lymphocytic infiltration. When compared with the adjacent normal skin, the dermal thickness was reduced and the dermal collagen appeared more compact. The sweat glands,
منابع مشابه
Linear atrophoderma of Moulin located on the face
Linear atrophoderma of Moulin (LAM) is a dermatosis characterized by hyperpigmented and depressed band-like lesions localized along the Blaschko lines. This dermatosis was described for the first time by Moulin et al. in five patients with similar characteristics in 1992 and referred to atrophoderma of Moulin, with referrance to the first publication [1,2]. Major characteristics of LAM are bein...
متن کاملLinear atrophoderma of Moulin: a case report and review of the literature
Linear atrophoderma of Moulin (LAM) is a rare dermatosis in childhood and early adolescence. The exact etiology of LAM is still obscure. Several treatment modalities were reported but none was consistently successful. We report a case of LAM in which a favorable outcome was obtained with topical calcipotriol. The relevant literature is also reviewed.
متن کاملLinear atrophoderma of Moulin: an underrecognized entity
Linear atrophoderma of Moulin (LAM) is an acquired skin condition that manifests in early childhood and adolescence. It likely represents a form of cutaneous mosaicism that presents with linear, hyperpigmented and atrophic lesions appearing on the trunk and limbs. Its clinical appearance varies and may closely resemble that of atrophoderma of Pasini and Pierini (APP) and linear scleroderma. LAM...
متن کاملAn unusual manifestation of linear atrophoderma of Moulin.
the pretibial areas. Erythema ab igne. Arch Dermatol 1990; 126: 386 ± 387. 4. Meffert JJ, Davis BM. Furniture-induced erythema ab igne. J Am Acad Dermatol 1996; 34: 516 ± 517. 5. Butler ML. Erythema ab igne, a sign of pancreatic disease. Am J Gastroenterol 1977; 67: 77 ± 79. 6. Ashby M. Erythema ab igne in cancer patients. J R Soc Med 1985; 78: 925 ± 927. 7. Arrington JH 3rd, Lockman DS. Therma...
متن کاملCongenital Atrophoderma of Pasini and Pierini
Idiopathic atrophoderma of Pasini and Pierini is a form of dermal atrophy of unknown etiology, usually affecting women during their adolescence and young adulthood. A 2-yr-old girl was presented with erythematous atrophic lesion on the right shoulder, which appeared from birth. The histologic findings were consistent with atrophoderma. This patient, to the best of our knowledge, is the first ca...
متن کامل